The potential of genetic approaches to cure diabetes is becoming increasingly promising, with breakthroughs on the horizon. On the 21st, the Biochip Shanghai National Engineering Research Center and Hangzhou Yiyuan Biotechnology Co., Ltd. jointly announced a significant development: the use of a mutated glucokinase gene to treat type 2 diabetes. This marks an important step forward in the field of gene therapy for metabolic disorders.
Glucokinase plays a crucial role in the body's glucose-sensing and regulatory system. After over a decade of in-depth research, scientists discovered that this enzyme can enhance glucose-stimulated insulin secretion, allowing the body to naturally regulate blood sugar levels. This approach targets the root cause of diabetes rather than just managing symptoms. However, challenges remain—such as the low activity of the natural glucokinase protein and the risk of severe hypoglycemia in experimental animals, which raised safety concerns.
To address these issues, researchers engineered a mutated version of the glucokinase gene. Preclinical trials in animal models have shown that this modified gene is both effective and safe in treating type 2 diabetes. The results suggest a promising future for glycemic control and potentially even long-term remission of the disease.
Globally, approximately 250 million people are affected by type 2 diabetes, and the number is growing by about 10% annually, with cases increasingly appearing in younger populations. In response, many countries are actively researching novel gene therapies that work through the body’s natural mechanisms to lower blood sugar. This study represents a pioneering effort in China, as no similar research has been previously documented through official channels. With continued progress, this innovative approach could revolutionize diabetes treatment in the years to come.
LED Down Light
This classification mainly includes the aluminum or zinc alloy die casting components using in LED Down Light area.
In the die casting process,higher specific pressure is required, so that higher filling speed can be obtained.which is helpful for alloy to overcome mold filling resistance.and effectively fill each part of the cavity.The Casting General Tolerance is Grade GB-CT4.
Process Technology: High pressure die casting,Shot Blasting,NC Machining,Spray Coating
Product Dimensions: Customized
Casting General Tolerance: Grade GB-CT4
Flow Processes: Die casting, Degating to remove the residual of the gate, Polishing and Deburring to remove the burrs, Polishing to remove the parting line, flash,CNC Turning, Cleaning, Packaging, Storaging, Shipping
Control Measure: Incoming Material Test, First Article inspection, Routing inspection, Final item inspection, and Outgoing quality control
Inspection Equipment: CMM, Caliper, Plug Gage, Screw Gauge
Application: Machinery Parts
Certificate: IATF16949:2016,ISO14001:2015,ISO45001:2018
Lead Time: 30-35 days
Trade Term: FOB Ningbo
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