American trials use light nanotechnology and biomolecules to treat cancer

Biomedical experts at the University of Texas Southwestern Medical Center and nanotechnology experts at the University of Texas at Dallas are experimenting with a new way to treat cancer by attaching antibody molecules that recognize cancer cells to tiny carbon nanotubes in near-infrared Under light irradiation, carbon nanotubes will heat up and kill cancer cells.

The relevant research results were published in the new issue of Zui's Proceedings of the National Academy of Sciences.
In this study, the researchers applied a single Cologne antibody to a specific target of lymphoid tumor cells on tiny carbon nanotubes. A single Cologne antibody is a biomacromolecule that binds to cancer cells; carbon nanotubes are very small cylinders of graphite carbon atoms that generate heat when exposed to near-infrared light. Near-infrared light can penetrate 1.5 inches (3.8 cm) inside the human tissue. Although the human eye can't see it, the night vision device can capture it. The TV remote control also emits control signals through near-infrared light.
In lymphocyte cancer cells, antibody-coated carbon nanotubes adhere to the surface of cancer cells. When they are exposed to near-infrared light, the carbon nanotubes begin to heat up, generating enough heat to "cook" the cancer cells. When the coated antibody is not associated with lymphoid tumor cells, the carbon nanotubes will neither adhere to the tumor cells nor kill them.
One of the authors of the paper, Dr. Alan Wittta, director of the Center for Cancer and Immunobiology at the Southwestern Medical Center at the University of Texas, believes that the attraction of this study is the use of near-infrared light to generate excessive heat because of the human biome Radiation absorption in the near-infrared range is weak, and once the carbon nanotubes adhere to the tumor cells, near-infrared light from the outside can safely pass through the normal tissue and kill the tumor cells. Vitta pointed out that this study proves that cancer cells can be killed exclusively in the laboratory. But even so, there is still much work to be done before this new treatment is extended to clinical research.
Currently, several research groups are engaged in research using carbon nanotube heating to kill cancer cells. Viterta's research* proves that both antibodies and carbon nanotubes retain their physical properties and functions by directional bonding to target cells and killing them. (Reporter Li Xuehua)

Core Keywords: Tumor Cell Lymphoma

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