Topical Antibiotics Pharmaceutical Raw Materials Mupirocin CAS 12650-69-0
Airbrush Spray Gun,Spray Gun,Airbrush Gun Haosheng Pneumatic Machinery Co., Ltd. , http://www.nb-tattoo.com
Product Name: Mupirocin
Synonyms: MUPIROCIN;MUPIROCIN CALCIUM;PSEUDOMONIC ACID;PSEUDOMONIC ACID A;(2s-(2-alpha(e;4-beta,5-alpha(2r*,3r*(1r*,2r*))))-3-beta;bactroban;nonanoicacid,9((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1
CAS: 12650-69-0
MF: C26H44O9
MW: 500.62
EINECS: 231-791-2
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Heterocycles;API;Inhibitors
Melting point : 77-780C
storage temp. : Under Inert Atmosphere
solubility : H2O: 12 mg/mL, soluble
Chemical Properties: White Crystalline Solid
Usage: antibacterial, antimycoplasmal, isoleucyl-tRNA synthetase inhibitor
Usage   : Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.
Usage   : Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.
Usage : vasodilator
Usage  : An antibiotic inhibitor of isoleucyl-tRNA synthetase .
Mupirocin Topical antibiotics
The crude drug of Bactroban ointment produced by the well-known domestic pharmaceutical company SmithKline is mupirocin which is a new type of local topical antibiotic and a kind of metabolic substance produced in the culture solution of pseudomonas fluorescence, that is, Pseudomonas A. Mainly through reversibly combined with isoleucine transfer RNA synthetase, this product can prevent the isoleucine incorporation and terminate the protein synthesis in cells containing isoleucine, leading to bacterial death. At low concentrations, this product has the inhibitory effect and at high concentrations, it has the bactericidal effect. This product is highly sensitive to a variety of gram-positive bacteria associated with skin infections, particularly staphylococcus aureus (including drug-resistant staphylococcus aureus) and streptococcus pyogenes; and it is also available for listeria monocytogenes and erythema erysipelothrix bacteria; it is generally not sensitive to gram-negative bacteria, but have some antibacterial effect on some Gram-negative bacteria such as E. coli, neisseria, haemophilus influenzae and Neisseria gonorrhoeae and is not sensitive to the majority of anaerobic bacteria and the normal flora of the skin and has low efficacy against fungi. Rate of occurrence is very low in vitro resistant mutants. After applied into the skin, this medicine can penetrate into the stratum corneum, but the absorption rate is very low. The binding rate of this drug and human serum protein is 95%. when absorbed, it is rapidly metabolized to an inactive substance single spore acid (Monic Acid) and excreted by the kidneys. The minimum inhibitory concentration of most sensitive staphylococcus is 0.01 ~ 0.25mg / L, that of sensitive streptococcus is 0.06 ~ 0.5mg / L, and that of listeriosis is 8mg / L. This product is more effective in vitro tests under acidic conditions than that under alkaline conditions. When human serum exists, activity of this drug reduce to 1/10 ~ 1/20.Â
Currently, in China, mupirocin is mainly and clinically used for the treatment of staphylococcus aureus and streptococcus caused by various infectious skin diseases: primary skin infections such as impetigo, folliculitis, and boils carbuncles etc; secondary skin infections such as eczema, atopic dermatitis, skin ulcers, surgical wounds, small burns, skin trauma; and other prevent infections such as small wounds, wound infections, and other sterilization venereal damage.
Mupirocin Uses
Topical antibiotics. This product is generally used for the inflammation of the skin, eczema, etc., or made into mupirocin ointment in the market.By reversibly binding to isoleucine transfer RNA synthetase, this product can prevent isoleucine incorporated so that the synthesis of all proteins in cells containing isoleucine can be stopped.
Â
Related Products
Specifications
Benzocaine CAS:94-09-7Â
Benzocaine hydrochloride CAS:23239-88-5Â
Tetracaine hydrochloride CAS:136-47-0
Procaine  CAS:59-46-1Â
Tetracaine CAS:94-24-6Â
Pramoxine Hydrochloride CAS:637-58-1
Procaine HCl CAS:51-05-8
Procainamide hydrochloride CAS : 614-39-1
Lidocaine CAS:137-58-6
Dibucaine hydrochloride CAS:61-12-1
Cinchocaine CAS:85-79-0
Prilocaine CAS:721-50-6
Propitocaine hydrochloride CAS:1786-81-8
Proparacaine hydrochloride CAS:5875-06-9
Lidocaine hydrochloride CAS:73-78-9
Articaine hydrochloride CAS:23964-57-0
Levobupivacaine hydrochloride CAS:27262-48-2
Ropivacaine hydrochloride CAS:132112-35-7
Bupivacaine CAS:2180-92-9
Bupivacaine hydrochloride CAS:14252-80-3
Mepivacaine hydrochloride CAS: 1722-62-9
DIOXOPROMETHAZINE HCL CAS: 13754-56-8
Topical Antibiotics Pharmaceutical Raw Materials Mupirocin CAS 12650-69-0
Product Name: Mupirocin
Synonyms: MUPIROCIN;MUPIROCIN CALCIUM;PSEUDOMONIC ACID;PSEUDOMONIC ACID A;(2s-(2-alpha(e;4-beta,5-alpha(2r*,3r*(1r*,2r*))))-3-beta;bactroban;nonanoicacid,9((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1
CAS: 12650-69-0
MF: C26H44O9
MW: 500.62
EINECS: 231-791-2
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Heterocycles;API;Inhibitors
Melting point : 77-780C
storage temp. : Under Inert Atmosphere
solubility : H2O: 12 mg/mL, soluble
Chemical Properties: White Crystalline Solid
Usage: antibacterial, antimycoplasmal, isoleucyl-tRNA synthetase inhibitor
Usage   : Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.
Usage   : Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.
Usage : vasodilator
Usage  : An antibiotic inhibitor of isoleucyl-tRNA synthetase .
Mupirocin Topical antibiotics
The crude drug of Bactroban ointment produced by the well-known domestic pharmaceutical company SmithKline is mupirocin which is a new type of local topical antibiotic and a kind of metabolic substance produced in the culture solution of pseudomonas fluorescence, that is, Pseudomonas A. Mainly through reversibly combined with isoleucine transfer RNA synthetase, this product can prevent the isoleucine incorporation and terminate the protein synthesis in cells containing isoleucine, leading to bacterial death. At low concentrations, this product has the inhibitory effect and at high concentrations, it has the bactericidal effect. This product is highly sensitive to a variety of gram-positive bacteria associated with skin infections, particularly staphylococcus aureus (including drug-resistant staphylococcus aureus) and streptococcus pyogenes; and it is also available for listeria monocytogenes and erythema erysipelothrix bacteria; it is generally not sensitive to gram-negative bacteria, but have some antibacterial effect on some Gram-negative bacteria such as E. coli, neisseria, haemophilus influenzae and Neisseria gonorrhoeae and is not sensitive to the majority of anaerobic bacteria and the normal flora of the skin and has low efficacy against fungi. Rate of occurrence is very low in vitro resistant mutants. After applied into the skin, this medicine can penetrate into the stratum corneum, but the absorption rate is very low. The binding rate of this drug and human serum protein is 95%. when absorbed, it is rapidly metabolized to an inactive substance single spore acid (Monic Acid) and excreted by the kidneys. The minimum inhibitory concentration of most sensitive staphylococcus is 0.01 ~ 0.25mg / L, that of sensitive streptococcus is 0.06 ~ 0.5mg / L, and that of listeriosis is 8mg / L. This product is more effective in vitro tests under acidic conditions than that under alkaline conditions. When human serum exists, activity of this drug reduce to 1/10 ~ 1/20.Â
Currently, in China, mupirocin is mainly and clinically used for the treatment of staphylococcus aureus and streptococcus caused by various infectious skin diseases: primary skin infections such as impetigo, folliculitis, and boils carbuncles etc; secondary skin infections such as eczema, atopic dermatitis, skin ulcers, surgical wounds, small burns, skin trauma; and other prevent infections such as small wounds, wound infections, and other sterilization venereal damage.
Mupirocin Uses
Topical antibiotics. This product is generally used for the inflammation of the skin, eczema, etc., or made into mupirocin ointment in the market.By reversibly binding to isoleucine transfer RNA synthetase, this product can prevent isoleucine incorporated so that the synthesis of all proteins in cells containing isoleucine can be stopped.
Â
Related Products
Specifications
Benzocaine CAS:94-09-7Â
Benzocaine hydrochloride CAS:23239-88-5Â
Tetracaine hydrochloride CAS:136-47-0
Procaine  CAS:59-46-1Â
Tetracaine CAS:94-24-6Â
Pramoxine Hydrochloride CAS:637-58-1
Procaine HCl CAS:51-05-8
Procainamide hydrochloride CAS : 614-39-1
Lidocaine CAS:137-58-6
Dibucaine hydrochloride CAS:61-12-1
Cinchocaine CAS:85-79-0
Prilocaine CAS:721-50-6
Propitocaine hydrochloride CAS:1786-81-8
Proparacaine hydrochloride CAS:5875-06-9
Lidocaine hydrochloride CAS:73-78-9
Articaine hydrochloride CAS:23964-57-0
Levobupivacaine hydrochloride CAS:27262-48-2
Ropivacaine hydrochloride CAS:132112-35-7
Bupivacaine CAS:2180-92-9
Bupivacaine hydrochloride CAS:14252-80-3
Mepivacaine hydrochloride CAS: 1722-62-9
DIOXOPROMETHAZINE HCL CAS: 13754-56-8