Petides 10mg/Vial Melanotan / Mt-1 for Whitening Sunscreen Melanotan 2

Model NO.: Melanotan / MT-1
Product Name: Melanotan-I
Assay: 98% Min
CAS No.: 51-42-3
Usage: Whitening Sunscreen
Odds: No Side Effects Positive
Grade: Pharmaceutical Grade
Trademark: Simeiquan
Transport Package: 10mg/Bottle
Specification: 98% min
Origin: China
HS Code: 2901100000
Model NO.: Melanotan / MT-1
Product Name: Melanotan-I
Assay: 98% Min
CAS No.: 51-42-3
Usage: Whitening Sunscreen
Odds: No Side Effects Positive
Grade: Pharmaceutical Grade
Trademark: Simeiquan
Transport Package: 10mg/Bottle
Specification: 98% min
Origin: China
HS Code: 2901100000
Melanotan-I
Melanotan-I, MT-I, Melanotan-1


Sequence: Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val
Molecular weight: 1647.4
Appearance: Sterile Filtered off-White lyophilized (freeze-dried) powder.
Formulation: The protein (1 mg/ml) was lyophilized with no additives.
Solubility: It is recommended to reconstitute the lyophilized Melanotan-I in sterile 1% acetic acid not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
Stability: Lyophilized Melanotan-I although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MT-I should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity: Greater than 98.0% as determined by RP-HPLC.
Usage: Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household

Melanotan 1 introduction

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

Melanotan-1 Mechanism of Action - How it Works!

Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

The Development of Melanotan 1

The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).

  Peptides Product list
 
                                            Peptides Product list
                                             Conventional Product in stock
MGF(2mg/bottle) PEG-MGF(2mg/bottle)
CJC-1295DAC 863288-34-0(2mg/bottle) CJC-1295(2mg/bottle)
PT-141 32780-32-8(10mg/bottle) Melanotan-I(10mg/bottle)
Melanotan-II (10mg/bottle) GHRP-2 158861-67-7(5mg/bottle)
GHRP-6 87616-84-0(5mg/bottle) Ipamorelin 170851-70-4(2mg/bottle)
Hexarelin  140703-51-1(2mg/bottle) Sermorelin 86168-78-7(2mg/bottle)
Oxytocin(2mg/bottle) TB500  75591-33-4(2mg/bottle)
pentadecapeptide BPC 157(2mg/bottle) Fragment 176-191 (2mg/bottle)
Triptorelin Acetate(2mg/bottle) Gonadorelin Acetate 34973-08-5 (2mg/bottle)
Tesamorelin 106612-94-6 (2mg/bottle) DSIP 62568-57-4(2mg/bottle)
Selank(5mg/bottle) AOD-9604 221231-10-3(1G / foil bag)
                                        Unconventional product (small stock)
Carbetocin Acetate 37025-55-1(1G / foil bag) Desmopressin acetate 16789-98-3(1G / foil bag)
EGF 62253-63-8 (1KG / fluorinated bottle) Eptifibatide 188627-80-7(1G / foil bag)
Thymosin α1 Acetate 62304-98-7(1G / polypeptide tube)
 

Bodybuilding Product list
 
                                        Bodybuilding Product list
                                                                       SERIES
Testosterone Enanthate 315-37-7 Testosterone Acetate1045-69-8
Testosterone Propionate 57-85-2 Testosterone Cypionate 58-20-8
Testosterone Isocaproate 15262-86-9 Testosterone Phenylpropionate 1255-49-8
Testosterone Undecanoate 5949-44-0 Testosterone Sustanon Testosterone Decanoate 5721-91-5
17-alpha-Methyl Testosterone 58-18-4 4- Chlorodehydromethyltestosterone 2446-23-3
Clostebol acetate 855-19-6
 
                                                                    
Nandrolone Decanoate (DECA)  360-70-3 Nandrolone Phenylpropionate 62-90-8
Methenolone Acetate (Steroids)   434-05-9 Methenolone Acetate 434-05-9
Stanolone 521-18-6
 
                                                                 
Trenbolone acetate(Finaplix)10161-34-9 Trenbolone enanthate 10161-33-8
Trenbolone Hexahydrobenzyl Carbonate  23454-33-3
 
                                                                         ANTI-ESTROGEN
Tamoxifen citrate 54965-24-1 clomifene citrate 50-41-9
107868-30-4 89778-27-8
                                                                Epinephrine & Thyroxine
L-Triiodothyronine(T3) 55-06-1 L-Thyroxine 51-48-9
L-Epinephrine Hydrochloride  55-31-2 Epinephrine hydrogen tartrate 51-42-3  
                                                                        Sex Enhancers
Tadalafil   171596-29-5 Vardenafil 224789-15-5
Avanafil 330784-47-9 Acetildenafil 831217-01-7
Dutasteride (Avodart)  164656-23-9 Finasteride 98319-26-7
Jinyang base Sexual Enhancement Ingredients
Crepis base
 
 
Our advantages 1,Years old factory:Simeiquan Biotechnology Co., Ltd. is a professional
raw powder factory in China for over 10 years, all powders are factory
directly supplying.

 
2,Export forceful:Our products have exported to Germany, Norway,
Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan,
Korea and many other countries, over 100kgs each month.

 
3,High passment:Professional team special for package and shipment
and staring on tracking code 24hours for customs pass guaranteed.
100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98%
pass to Germany, Russia, Australia, New Zealand.

 

4,Fast delivery :Most of powders are in stock, Chargeable samples are
available, Could be shipped out within 24hours.High quality, good price,
fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.


 
5,Flexible price:A discount would be given when you make a large order.

 
6,Good after-sale service:Warm after-sale service for you 24/7. Any of
your question would be solved for the first as soon as possible
Packaging & Delivery We have professional team for package and shipment. Special way to
ship 100 grams to 100kg powders at one time to your country. Fast and
discreet shipment could be arranged for customs pass Guaranteed.

Offer semi-finished oral liquid( (Dianabol)   Clomifene citrate (Clomid) )

Product Tags:Melanotan-I,Melanotan-II,75921-69-6
Petides 10mg/Vial Melanotan / Mt-1 for Whitening Sunscreen Melanotan 2 Melanotan-I
Melanotan-I, MT-I, Melanotan-1


Sequence: Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val
Molecular weight: 1647.4
Appearance: Sterile Filtered off-White lyophilized (freeze-dried) powder.
Formulation: The protein (1 mg/ml) was lyophilized with no additives.
Solubility: It is recommended to reconstitute the lyophilized Melanotan-I in sterile 1% acetic acid not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
Stability: Lyophilized Melanotan-I although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MT-I should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity: Greater than 98.0% as determined by RP-HPLC.
Usage: Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household

Melanotan 1 introduction

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

Melanotan-1 Mechanism of Action - How it Works!

Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

The Development of Melanotan 1

The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule "Melanotan" (later Melanotan-1).

  Peptides Product list
 
                                            Peptides Product list
                                             Conventional Product in stock
MGF(2mg/bottle) PEG-MGF(2mg/bottle)
CJC-1295DAC 863288-34-0(2mg/bottle) CJC-1295(2mg/bottle)
PT-141 32780-32-8(10mg/bottle) Melanotan-I(10mg/bottle)
Melanotan-II (10mg/bottle) GHRP-2 158861-67-7(5mg/bottle)
GHRP-6 87616-84-0(5mg/bottle) Ipamorelin 170851-70-4(2mg/bottle)
Hexarelin  140703-51-1(2mg/bottle) Sermorelin 86168-78-7(2mg/bottle)
Oxytocin(2mg/bottle) TB500  75591-33-4(2mg/bottle)
pentadecapeptide BPC 157(2mg/bottle) Fragment 176-191 (2mg/bottle)
Triptorelin Acetate(2mg/bottle) Gonadorelin Acetate 34973-08-5 (2mg/bottle)
Tesamorelin 106612-94-6 (2mg/bottle) DSIP 62568-57-4(2mg/bottle)
Selank(5mg/bottle) AOD-9604 221231-10-3(1G / foil bag)
                                        Unconventional product (small stock)
Carbetocin Acetate 37025-55-1(1G / foil bag) Desmopressin acetate 16789-98-3(1G / foil bag)
EGF 62253-63-8 (1KG / fluorinated bottle) Eptifibatide 188627-80-7(1G / foil bag)
Thymosin α1 Acetate 62304-98-7(1G / polypeptide tube)
 

Bodybuilding Product list
 
                                        Bodybuilding Product list
                                                                       SERIES
Testosterone Enanthate 315-37-7 Testosterone Acetate1045-69-8
Testosterone Propionate 57-85-2 Testosterone Cypionate 58-20-8
Testosterone Isocaproate 15262-86-9 Testosterone Phenylpropionate 1255-49-8
Testosterone Undecanoate 5949-44-0 Testosterone Sustanon Testosterone Decanoate 5721-91-5
17-alpha-Methyl Testosterone 58-18-4 4- Chlorodehydromethyltestosterone 2446-23-3
Clostebol acetate 855-19-6
 
                                                                    
Nandrolone Decanoate (DECA)  360-70-3 Nandrolone Phenylpropionate 62-90-8
Methenolone Acetate (Steroids)   434-05-9 Methenolone Acetate 434-05-9
Stanolone 521-18-6
 
                                                                 
Trenbolone acetate(Finaplix)10161-34-9 Trenbolone enanthate 10161-33-8
Trenbolone Hexahydrobenzyl Carbonate  23454-33-3
 
                                                                         ANTI-ESTROGEN
Tamoxifen citrate 54965-24-1 clomifene citrate 50-41-9
107868-30-4 89778-27-8
                                                                Epinephrine & Thyroxine
L-Triiodothyronine(T3) 55-06-1 L-Thyroxine 51-48-9
L-Epinephrine Hydrochloride  55-31-2 Epinephrine hydrogen tartrate 51-42-3  
                                                                        Sex Enhancers
Tadalafil   171596-29-5 Vardenafil 224789-15-5
Avanafil 330784-47-9 Acetildenafil 831217-01-7
Dutasteride (Avodart)  164656-23-9 Finasteride 98319-26-7
Jinyang base Sexual Enhancement Ingredients
Crepis base
 
 
Our advantages 1,Years old factory:Simeiquan Biotechnology Co., Ltd. is a professional
raw powder factory in China for over 10 years, all powders are factory
directly supplying.

 
2,Export forceful:Our products have exported to Germany, Norway,
Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan,
Korea and many other countries, over 100kgs each month.

 
3,High passment:Professional team special for package and shipment
and staring on tracking code 24hours for customs pass guaranteed.
100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98%
pass to Germany, Russia, Australia, New Zealand.

 

4,Fast delivery :Most of powders are in stock, Chargeable samples are
available, Could be shipped out within 24hours.High quality, good price,
fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.


 
5,Flexible price:A discount would be given when you make a large order.

 
6,Good after-sale service:Warm after-sale service for you 24/7. Any of
your question would be solved for the first as soon as possible
Packaging & Delivery We have professional team for package and shipment. Special way to
ship 100 grams to 100kg powders at one time to your country. Fast and
discreet shipment could be arranged for customs pass Guaranteed.

Offer semi-finished oral liquid( (Dianabol)   Clomifene citrate (Clomid) )

Product Tags:Melanotan-I,Melanotan-II,75921-69-6
Petides 10mg/Vial Melanotan / Mt-1 for Whitening Sunscreen Melanotan 2

with transverse stolons. Leaves 3-11; leaf blade ovate, slightly leathery; petiole glabrous. Scapes yellow-green, narrowly ovate, apical apex; petals nearly lanceolate, apex acuminate, Middle slightly widened, with honey groove; stamens long only about 1/2 of the petals; anthers yellow, filaments narrowly linear; style slightly curved. Oval oblong, carpels stalked puberulent. March-April flowering, April-June results. Specialty Chongqing pillars yellow water. Health elevation of 1600-2200 meters between the mountain forest, often cultivated, wild rare. Rhizome is a famous traditional Chinese medicine ("Coptis"), with berberine, Coptidis base, Coptis base, tetrandrine and other alkaloids, can cure acute conjunctivitis, acute bacillary dysentery, acute gastroenteritis, hematemesis, Embolism.

Crude Herbs

Crude Herbs,Berberine Coptis,Raw Herbs Radix Coptis,Herbs Radix Coptis

Chongqing Taisun Pharmaceutical Co., Ltd. , http://www.taisuncoptis.com