Irrational use of reproductive hormones

Infertility is a common and frequently occurring disease in the aquaculture industry. Treating infertility due to ovarian abnormalities with reproductive hormones is effective and effective. However, in clinical practice, some unreasonable medications occur from time to time. The following are the common 4 cases of irrational drug use.
1, do not know the physiological function of hormones, arbitrarily increase the dosage. If there is a young estrus in the household, the breeding staff is inseminated. After the direct inspection of the breeder, the cow is determined to be an ovarian cyst and needs to be treated. The breeder then injects three boxes (30 sticks) of chlorine into the cow. Enol. Tell the owner 7 days after the heat. After 7 days, the cow had no estrus, milk was down, and a few kilograms of milk per day could be squeezed. After a large dose of hormone treatment, no estrus occurred again, resulting in lifelong infertility.

Cloprostenol is a tradename for prostaglandins, which has two major physiological functions. One is the dissolution of the corpus luteum, and the other is the promotion of uterine contractions associated with childbirth activity. It is mainly used clinically for the treatment of persistent corpus luteum, or simultaneous estrus and delivery at the same time.

Ovarian cysts are divided into two cases: one is a corpus luteum cyst, and the other is a follicular cyst. If it is a corpus luteum cyst, the cow will not be estrus due to the continued secretion of progesterone. If it is a follicular cyst, because the follicle produces a large amount of estrogen in the inner membrane, the cow is in a state of sexual excitement for a long period of time. Treat progesterone hormones for corpus luteum cysts, 2 to 3 at a time, observe for 3 to 5 days, and if there is no response, inject once more. Follicle cysts due to the performance of Mu Xiong mad, can first use large doses of progesterone against estrogen, inhibit follicular development, or use LH to promote ovulation. In short, three boxes of chloroprostaglandol cannot be used anyway. The above case is normal estrus, because it does not show madness. In general young cattle, due to the large amount of hormones secreted, the follicles in estrus are larger than the follicles produced in cattle, which is a normal phenomenon and does not require treatment.

2. It is not clear half-life, prolong drug use time. There was a shepherd dog that was inactive during the estrus season. The veterinarian used genital hormone to induce estrus. He selected PMSG 300IU once a day for 7 days.

PMSG is pregnant serum, and its physiological function is to promote follicular development. Clinically used to treat follicular static or superovulation. However, it has a long half-life, and there is an effective concentration in the blood for 5 to 7 days. Each course of treatment will be injected once, without daily injection.

3, the injection time is irrational. Some veterinarians treat ovulation delays and choose to push Pai No. 3. They do not use heat to make injections. They don't pay attention when they are mated. Facilitate the third row is the luteinizing hormone release hormone D - tryptophan analogues, its physiological function is to promote further follicle maturation, ovulation and promote the formation of the corpus luteum. The correct method of use is to give injections 4 hours before breeding or at the time of mating.

4. Treatment of infertility with estradiol. Estradiol is an estrogen, its physiological function is to promote the estrus performance of the estrus and a series of physiological changes in the reproductive tract, such as the female vulva inflamed, increased secretions, squeaking, and accepting crawling. It has no effect on follicular development and it has no effect in treating infertility.

Professional breeders all know that using fertility hormones to treat infertility pays attention to the dose and the timing of injection, because trace amounts of reproductive hormones in the animal body can cause great physiological changes. When long-term high-dose fertility hormones are used, not only will they not achieve treatment. The effect may even have the effect of inhibiting reproductive function.

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