Clinical Diagnosis and Prevention of Transmissible Gastroenteritis in Pigs
Transmissible gastroenteritis is a highly contagious gastrointestinal infection. With the main features of autumn beginning, winter and spring intensification and summer less, vomiting, watery diarrhea and dehydration are the main clinical features. Pigs of all ages can be affected. The incidence and mortality of the pigs are the highest, and the incidence and mortality of adult pigs are less. The occurrence and prevalence of the disease will cause great losses to the development of the pig industry in China. It should arouse the attention of the majority of scientific research workers and pig farms. First, the pathogen Transmissible gastroenteritis virus belongs to the coronavirus coronavirus genus. The virus exists in various tissues, body fluids, and excretions of pigs, but the duodenum, jejunum, and mesenteric lymph nodes of the diseased pigs have the highest toxic content. Only one serotype of porcine transmissible gastroenteritis is associated with porcine hemagglutinating encephalomyelitis virus and porcine epidemic diarrhea virus, and has an antigen-cross-relationship with canine coronavirus and feline infectious peritonitis virus. Cats are considered carriers and communicators of the transmissible gastroenteritis virus. The vast majority of pig farms should be disinfected with fewer dogs and cats. Second, popular features The occurrence and prevalence of this disease is mainly concentrated in the winter and spring seasons, while the other seasons are less. This may be related to the temperature and humidity and lighting conditions required for virus survival and spread; it is related to the susceptibility of pigs (some immunosuppressive diseases, congenital stunting of pigs, etc.); and it is related to human behavioral factors (some pigs in the north Farms and even some large-scale pig farms only pay attention to keep warm in the winter and spring season, do not pay attention to ventilation and disinfection, ammonia is too concentrated, coupled with moldy feed, resulting in increased incidence of pigs; with the dog, cat and breeding pig perennial Poisoning is related to detoxification, which is widely endemic in new epidemic areas and has a high incidence rate and high mortality rate, while the old epidemic area is correspondingly lower and is endemic or intermittently endemic. Third, clinical symptoms The incubation period of the disease is short and spreads rapidly. The dead pigs were dehydrated, the skin was dark purple and stiff and spread across the pig farm. The first disease of the piglets was characterized by vomiting, ash [shielded] watery diarrhoea and rapid dehydration. Among these cases, the most common form of suckling pigs was wasting and death (up to 100%). The immature breast-feeding pigs were emaciated, unpainted and unsteady. Finishing pigs have rough hair, dark colors, lack of elasticity due to dehydration, and the symptoms of anorexia, vomiting, and diarrhea are not obvious and are transient. The incidence of individual pregnant sows can cause miscarriage. After the onset of lactating sows, the occurrence of high temperatures, anorexia, lack of milk or no milk, but also exacerbated the death of suckling pigs. Undigested curd or raw material was found in the feces of the affected pigs at all stages, and the stench was unpleasant. Fourth, pathological features The necropsy of the nurse pigs and fattening pigs mainly manifested as acute catarrhal gastroenteritis. The stomach was filled with undigested curd or mixed with [shielded] light green bile feed. The gastric fundal mucosa was congested and bleeding. Red cloth; Intestinal gas or gray [shielded] feed, especially the intestinal wall of the jejunum is thin and transparent, lacking in the elasticity; mesenteric lymph nodes are swollen and swollen; some pigs have spots on the back of the spleen, protruding from the surface, kidneys, lungs There are different degrees of swelling and interstitial widening. Small intestinal villi become shorter or atrophy. V. Diagnosis Comprehensive diagnosis based on epidemiology, clinical symptoms and pathological changes. Note that it is distinguished from E. coli disease, rotavirus disease, epidemic diarrhea, etc. E. coli disease mainly refers to yellow pigs and white psoriasis. Rotavirus disease mainly occurs in 2 months old pigs. Epidemic diarrhea occurs earlier than infectious gastroenteritis. It can also be distinguished by serological, histological microscope observations, and the like. Six, comprehensive prevention (a) Preventive measures. 1. Immunity. Do a good job of immunizing pigs with transmissible gastroenteritis vaccines before winter. 2. Prevention. In regions where there has been no epidemic of transmissible gastroenteritis, attention has been paid to the introduction of safety; there are pig farms that are endemic in this area, banned dogs and cats on the premises, and regular disinfection; pay attention to feed hygiene and the disinfection of transport vehicles. 3. Drug prevention. Can be used Zhongsheng Hao (vegetal hemagglutinin), powerful double Qishao (compounds of pefloxacin mesylate) every 2 weeks according to the instructions of spices fed 1 to 2 days. (b) Treatment. At present, there are no specific drugs for the treatment of transmissible gastroenteritis in pigs. However, the following methods are effective for preventing concurrent infections and healing. 1. Take 100 grams of soluble powder from Zhongsheng Astragalus polysaccharide and 100 kg of water. Let the pigs drink freely for 3 to 5 days. 2. Using the Zhongsheng nickname and the potent double Qishu or fluocin in a 0.1% ratio, the sick pigs were allowed to eat for 3 days. 3. With Yawei gentamicin, antiviral No. 1 intramuscular injection, 1 or 2 times a day. To symptomatic treatment, to prevent dehydration and acidosis and secondary infection as the principle of treatment, can achieve better therapeutic effect.
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