Chinese scholars in the United States invent "nano-trap"
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If it can be successfully promoted to the virus field, it is expected to be used for large-scale monitoring of SARS virus. The Chinese scientists from the United States who work for the University of Texas Agricultural Machinery at Xinhua News Agency have recently developed a device called “nano-trap†that can be used to infect bacteria. The "screaming" quickly judges the type of bacteria. If this technology can be successfully extended to the virus, it will be expected to be used for large-scale monitoring of SARS virus. Professor Chen Cheng of the Department of Electronic Engineering at Texas A&M University stated in an e-mail to the reporter that when bacteria are infected with bacteriophage, bacteriophages will make a hole in the bacterial cell membrane and inject their own genetic material into the bacteria. After dozens of bacteriophages have been replicated in bacteria, bacterial cells break down and new-generation bacteriophages emerge. When the phage injects genetic material into the bacteria, the ions in the bacteria's cells are released, changing the surrounding electric field. According to this situation, Cheng Hao and other scientists designed a "nano-well." The key device for this small device is a low-cost chip, but it can detect the ion activity of individual bacteria in the vicinity. When the bacteria are attacked by phage to release ions, the corresponding voltage noise will appear in the “nano-wellâ€. The characteristic of this voltage noise is completely different from the background noise, as if it were a "screaming" after a cell injury. Because each phage only infects the only species that corresponds to it, scientists can use different bacteriophages to detect bacteria through whether the “nano trap†hears bacteria “screamingâ€. In the March issue of the American Journal of Biophysics and Chemistry, scientists at Texas A&M University stated that they have used "nano traps" to test E. coli. The success rate is 100%, and the detection process is only a few. In minutes, the operation is very simple. However, existing bacterial detection techniques often require hours or even days for colony culture or DNA replication, which can be accomplished by trained personnel using expensive equipment. Experts believe that due to the rapidity and low cost of the “nano trap†technology, it is expected to be widely used in the fields of medicine, agriculture, environmental protection, and anti-biological weapons attacks. At present, researchers are researching and extending the "nano trap" technology to the field of virus detection. If successful, this technology is expected to be used for the large-scale monitoring of viruses such as SARS.